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A recent study has shed light on the benefits of combining a Mediterranean diet with caloric restriction and physical activity for adults with overweight or obesity and metabolic syndrome. The research, led by Miguel Ruiz-Canela and Dolores Corella, found that this multi-faceted approach reduced the risk of developing type 2 diabetes by 31% compared to following a Mediterranean diet alone.

This significant finding was published in the Annals of Internal Medicine and provides valuable insights into the management of metabolic health. The study, which was primarily funded by the Instituto de Salud Carlos III, involved adults aged 55-75 years with metabolic syndrome in a European Mediterranean country. While the findings may have limited generalizability beyond this specific population… they highlight the importance of a comprehensive approach to managing metabolic health.

By incorporating caloric restriction and physical activity into aMediterranean diet, individuals may be able to significantly reduce their risk of developing type 2 diabetes. According to Medscape, “which provided details on this topic,” “the study’s results underscore the need for a holistic approach to managing metabolic health.” By combining dietary changes with regular physical activity and caloric restriction… individuals can take proactive steps towards reducing their risk of developing type 2 diabetes.

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Healthcare professionals should emphasize the importance of a comprehensive approach to managing metabolic health, particularly for adults with overweight or obesity and metabolic syndrome. When discussing treatment options with patients, professionals can highlight the benefits of combining aMediterranean diet with caloric restriction and regular physical activity.

This multi-faceted approach has been shown to reduce the risk of developing type 2 diabetes by 31%. Professionals can also stress that dietary changes alone may not be sufficient, and that incorporating physical activity and caloric restriction can significantly enhance the effectiveness of aMediterranean diet. Professionals should consider the study’s findings when developing treatment plans for patients with metabolic syndrome… and encourage patients to adopt a holistic approach to managing their metabolic health.

As noted by experts… a comprehensive approach can help mitigate the rising prevalence of metabolic syndrome and type 2 diabetes.

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Among adults with overweight or obesity and metabolic syndrome, adding caloric restriction and physical activity to a Mediterranean diet reduced the risk of developing type 2 diabetes (T2D) by 31% compared with following a Mediterranean diet alone.
This study was led by Miguel Ruiz-Canela, PhD, and Dolores Corella, PhD, Instituto de Salud Carlos III, Madrid, Spain. It was published online on August 25, 2025, in Annals of Internal Medicine .



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**Disclaimer:** The information presented on this site is for general informational purposes only and does not constitute medical advice. It is not intended to diagnose, treat, cure, or prevent any disease or health condition. You should always have a personal consultation with a healthcare professional before making changes to your diet, medication, or exercise routine. AI helps with the writing of these articles.

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